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MICROSYSTEM AND LAB ON A CHIP (SPRING 2016)

MATERIALS IN LIFE (SUMMER 2016)

MICROSYSTEM AND LAB ON A CHIP (FALL 2016)

Publications

In Submission:

- Photoactive drug-release from rolled-up microstructures: Static microtubes and self-propelled microjet engines (2015)
 
- TiO2 nanosheets synthesized by atomic layer deposition for a high photocatalytic performance (2015)

 
Published:

 
21) Y. F. Mei, G. S. Huang, A.A.Solovev, E. B. Ureña, I. Mönch, F. Ding, T. Reindl, R. K. Y. Fu, P. K. Chu, and O. G. Schmidt. Versatile Approach for Integrative and Functionalized Tubes by Strain Engineering of Nanomembranes on Polymers. ADVANCED MATERIALS, 20, 4085–4090, (2008). [JOURNAL COVER IMAGE]. Featured in: Frankfurter Allgemeiner Zeitung, IFW Highlight, Pro-physik.de, PM Magazine, Zeit Wissen Magazine, Bild Zeitung, Magazines: Welt der Physik, Spektrum der Wissenschaft.
 
20) A.A.Solovev, S. Sanchez, M. Pumera, Y.F. Mei and O. G. Schmidt. Magnetic Control of Catalytic Microbots for the Delivery and Assembly of Microobjects, ADVANCED FUNCTIONAL MATERIALS, 20, 15, 2430 (2010). [JOURNAL COVER IMAGE]. Featured in: RSC Chemistry World, Nanowerk Spotlight
 
19) A.A. Solovev, Y.F. Mei, E. B. Ureña, G. Huang, and O. G. Schmidt. Catalytic Microtubular Jet Engines Self-propelled by Accumulated Gas Bubbles, SMALL, 5, 1688 (2009). [JOURNAL COVER IMAGE]
 
18) Y. F. Mei, A.A.Solovev, S. Sanchez, O.G. Schmidt. Rolled-up Nanotech on Polymers: From Basic Perception to Self-Propelled Catalytic Microengines, CHEMICAL SOCIETY REVIEWS, 40, 2109 (2011). [JOURNAL COVER IMAGE] Featured in: derStandard.at, LiLipuz.de, Blick.ch
 
17) W. Xi,# A.A. Solovev,# A.N. Ananth, D. H. Gracias, S. Sanchez, O. G. Schmidt. Magnetic Micro- drillers: Towards Minimally Invasive Surgery. NANOSCALE, 5, 1294 (2013).
[JOURNAL COVER IMAGE] # - authors with equal contributions
 
16) A.A. Solovev, S. Sanchez, O.G. Schmidt. Collective Behaviour of Self-Propelled Catalytic Micromotors, NANOSCALE, 5, 1284 (2013)
 
15) G. Wang, A.A.Solovev, G. Huang, M. Maitz, N. Huang, Y.F. Mei. Dynamic curvature control of rolled-up metal nanomembranes activated by magnesium. JOURNAL of MATERIALS CHEMISTRY, 22, 12983, (2012)
 
14) A.A. Solovev, W. Xi, D. H. Gracias, S. Harazim, C. Deneke, S. Sanchez, O.G. Schmidt. Self- Propelled Nanotools, ACS NANO, 6 (2), 1751 (2012)
 
13) A.A. Solovev, E. Smith, Carlos C. Bof ' Bufon, S. Sanchez, O. G. Schmidt. Light-Controlled Propulsion of Catalytic Microengines, ANGEWANDTE CHEMIE INTERNATIONAL EDITION, 50 (46), 10875–10878 (2011)
 
12) S. Sanchez, A.A.Solovev, S. Harazim, Ch. Deneke, Y. F. Mei, O. G. Schmidt. Smallest Man-Made Jet Engine, CHEMICAL RECORDS, 11 (6), 367 (2011)
 
11) A.A. Solovev, S. Sanchez, Y. F. Mei, O.G. Schmidt. Tunable Catalytic Tubular Micropumps operating at Low Concentration of Hydrogen Peroxide, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 13, 10131 (2011)
 
10) U. Vogl, A. Saß, F. Vewinger, M. Weitz, A.A. Solovev, Y. F. Mei, O. G. Schmidt. Light Confinement by a Cylindrical Metallic Waveguide in a Dense Buffer Gas Environment. PHYSICS REVIEW A, 83, 053403 (2011)
 
9) S. Sanchez, A.A. Solovev, S. Harazim and O.G. Schmidt. Microbots swimming in the Flowing Streams of Microfluidic Channels, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133 (4), 701 (2011)
 
8) S. Sanchez, A.A.Solovev, S. Schulze and O. G. Schmidt. Controlled Manipulation of Multiple Cells using Catalytic Microbots, CHEMICAL COMMUNICATIONS, 47, 698 (2011). Featured in: RSC Chemistry World
 
7) S. Sanchez, A.A. Solovev, Y.F. Mei and O.G. Schmidt. Dynamics of Biocatalytic Micro-Engines mediated by Variable Friction Control, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132, 13144 (2010). Featured in: Nanowerk Spotlight, ChemViews Magazine, RSC Chemistry World
 
6) A.A. Solovev, Y.F. Mei and O.G. Schmidt. Catalytic Micro-Strider at the Air- Liquid Interface, ADVANCED MATERIALS, 22, 4340 (2010). Featured in: Materialsviews; Nanowerk Spotlight
 
5) S. Sanchez, A.A.Solovev, E. J. Smith, C. C. Bof’ Bufon, V. M. Fomin, A. N. Ananth, M. Viehrig, O. G. Schmidt. External Sources for controlling the propulsion of self-propelled microjet engines. ANNUAL REPORT. IFW Dresden (2011)
 
4) S. Sanchez, A.A.Solovev, S. Schulze, S. M. Harazim, Y. F. Mei and O. G. Schmidt. Catalytic and Biocatalytic Microbots. ANNUAL HIGHLIGHT. IFW Dresden, 39–41 (2010)
 
3) A.A.Solovev, Y. F. Mei, and O.G. Schmidt. Nanorocket Epxeriments for High School. Dechema: Chemical & Biological Society, BROCHURE FÜR HOCHSCHULE, Marburg (2010)
 
2) A. A. Solovev, S. Sanchez, Y. F. Mei and O. G. Schmidt. Wireless Control of Tubular Catalytic Microbots for the Transportation and Delivery of Microobjects. ANNUAL REPORT. IFW Dresden (2009)
 
1) A. A. Solovev, Y. F. Mei, S. Harazim, C. Deneke, G. S. Huang, O. G. Schmidt. Self-Propelled Microjets at Low Reynolds Number. ANNUAL HIGHLIGHT, 44–46, IFW Dresden (2008)
 
BOOK CHAPTERS
 
S. Sánchez, W. Xi, A. A. Solovev, L. Soler, V. Magdanz, O. G. Schmidt. Tubular Micronanorobots: Smart Design for Bio-related Applications. Small-Scale Robotics. From Nano-to-Millimeter-Sized Robotic Systems and Applications. Lecture Notes in Computer Science. Springer, 8336, 16-27, 2014.

 

 

NEWS! NEWS! NEWS!

We search for new talented and motivated students interested to do research at the cutting edge of nanotechnology!
We collaborate with top groups including MIT, Harvard, University of Toronto.

Prof. Solovev won prestigeous "Dawn program" grant from Shanghai City (03.2016)
Prof. Solovev was invited for a meeting with Prime Minister of China in the Great People Hall Beijing (02.2016)
Prof. Solovev was awarded "1000 Talent" high-level foreign expert grant 3 Million RMB (09.2015)

Welcome to our new students: 
Mauricio Rocktäschel, Yi Chen

For PhD, postdoc positions contact:
Prof. Alexander Solovev
solovev@fudan.edu.cn
asolovev@gmail.com

Materials Science Department
220 Handan Road
Fudan University
Welcome to our research group!

Nature’s nanomachines support life on Earth during millions of years.  We live in the era of machines’ miniaturization and tomorrow’s technological revolution will be the nanomachinery industry. Discovery of nanojet engines capable to self-propel faster than the fastest bacteria was enabled by 3-D nanomembranes technology. If one thinks about nanomachines the first questions to ask: from where the power comes to autonomous nanomachine? Is there a tank with a fuel? Can nanoengine rely on inertia? How to achieve a high motive force in highly viscous environments? How to overcome Brownian diffusion? How to make a complex nanomachine? What are potential applications? Biological cells and motor proteins solved these problems millions of years ago, these “dream nanomachines” work collectively by converting local chemical energy into movement and useful operations. First principles we learn from nature, at the nanoscale there is no need to carry a tank with a fuel - fuel is everywhere. We need small machines to explore thenanoworld”

Selected Invited Talks: 

- How Chinese Universities become World Class without losing their National Characteristics? Education Conference, Shaanxi Province, China, 06.2016
- Nanomotors Workshop, Shenzhen, China (2016)
- Conference, AVS Thin Films, Fudan University, Shanghai, China (2015)
- The Smallest Man-Made Jet Engine, ChiNANO, Suzhou, China (2015)
- CO2 Conversion to Fuels using Photo-Fuel-Cell, Toronto, Canada (2015)
- Conference, “Micro- and Nanomachines”, Hannover, Germany (2014)
- "Challenges and Perspectives of a 3-D Nanoworld", Skolkovo Institute of Technology, Moscow, Russia (2014)
- “The Smallest man-made Jet Engine", Massachusetts Institute of Technology (MIT), Boston, USA (2013)
- "Catalytic Nanojet Engines“, Ludwig Maximillians University Munich, Germany (2011)
- “Synthetic Catalytic Nanomachines”, Max Planck Institute for Biochemistry, Munich, Germany (2011)
- “Catalytic Microjet Engines”, Physics Department, Technical University of Munich, Germany (2011)
- "Self-Assembled Microjet Engines", DSM Science and Technology Awards, Switzerland (2008)
- “Biofunctionalized Thin Film SOI Transistors for Biosensing”. Columbia University, New York, USA (2004). 
Prof. Alexander A. Solovev
PhD: Germany; Postdoc: TU Munich, Max Planck Institute, University of Toronto
, Canada

1000 Talent Award, Fudan University, Shanghai, P. R. China, 2015
Humboldt Feodor Lynen Fellowship for Research Project at University of Toronto, Canada, 2015
Max Planck Fellowship, Institute for Intelligent Systems, Stuttgart, Germany, 2014
DAAD Prize for International Scholar, TU Munich, Germany, 2012
Guinness World Record for “the Smallest Man-Made Jet Engine”, 2011
DSM Science and Technology Award, Zürich, Switzerland, 2009
FIRST-Place Award of the Country, Students Olympiad in Subject: “Theoretical Mechanics”, Kyrgyzstan, 2001
    Teaching
  • We believe that education must be not a heavy duty, but a learning process to enjoy
  • Join our Microsystem and Lab-on-a-Chip, Materials in Life Courses

Selected Journals Cover Images:
Collaborators
    Research
  • Nanotechnology helps to break artificial boundaries between disciplines
  • Our group is interested in both deep fundamental questions and specific engineering applications







Nanomachines
Clean Energy
Self-Assembly
Microfluidics
Non-Equilibrium Systems
Collective behavior
Research
People

Course Code:

MATE130086.01

Course Title:

Microsystem and Lab-on-a-Chip

Instructor Name:

Alexander Solovev

Affiliated Institution:

 

Venue:

West GuangHua Building Room 302

Days & Time:

Wednesday 8:00-8:45; 8:55-9:40

E-Mail:

solovev@fudan.edu.cn

Course Goals and Objectives

Upon completion of this course, students will learn: basics of microfluidics, materials and fabrication technologies, multifunctional microdrops, on-chip: biosensors, healthcare and diagnostics; on-chip: energy generation, harvesting and conversion; nanoscale effects of physics, chemistry, materials, mechanics, electronics, heat, photonics; micro-electro-mechanical systems; materials self-assembly and self-organization paradigms; bioinspired materials; self-propelled micro/- nanomotors, engines, gears and pumps; chaos and reductionism; integration of properties, effects and functions at the nano-, micro,- mesoscale; science of inventive problem solving. Moreover, students will chose important problem/technology and learn how to use scientific methodology to overview, analyze and use data and prepare own review type of written report, followed by technical oral presentation for a broad public.

Moreover, students will be able to:

   - Understand main advantages of microfluidics (new materials, lab-on-a-chip);

- Understand scaling laws required for practical work with nano/- materials and devices;

- Be able to understand modern micro- and nanomaterials, methods of fabrication, characterization and their unique properties;

- Develop problem solving skills, information analysis and develop individual research idea;

- Develop professional presentation skills;

We demonstrated the Smallest Man-Made Jet Engine:
Ms. Shi Bingyao

Maro Rocktaeschel

Dr. Yan
Research manager
Professor Geoffrey Ozin
Chemistry Department
University of Toronto, Canada


Professor David Gracias
Chemical and Biomedical Engineering
Johns Hopkins University, USA


Professor John Gibbs
Department of Physics and Astronomy
Northern Arizona University



www.nanowizardry.info
graciaslab.johnshopkins.edu
//www.physics.nau.edu/~gibbs
//pf.is.mpg.de/
Professor Peer Fischer
Max Planck Institute for Intelligent Systems
Stuttgart, Germany
Dr. Denys Makarov
Helmholz-Zentrum Dresden-Rossendorf
Germany

www.smartsensorics.eu
Bachelor students
Summer students
Postdoctoral scientists
Master students
Mr. Yi Chen
Dr. Huanpo Ning

We demonstrated autonomous catalytic microtubes (microjet engines) with tunable diameters ranging from micro- to nanoscale and lengths from 50 μm to 1 mm. These results open the door to effective microengines and represent the entry in the Guinness Book of World Records for “the smallest man-made jet engine.

Several attractive methodologies of machine-based functions at the micro- and nanoscale are shown. For instance, catalytic Ti/Cr/Pt microjets, which are integrated on a planar substrate, can operate as “on chip” chemical micropumps by decomposition of hydrogen peroxide fuel into oxygen bubbles and water. When released from a substrate, microjets self-propel autonomously in solution. The incorporation of ferromagnetic layer (Fe) into the rolled-up geometry enables their remote control using external magnetic field. Such microjets were used to load, transport, deliver and assemble multiple cargo particles, including biological cells in bulk solutions and microfluidic channels.

It was demonstrated that for microjets that are fixed to or self-propelled above a platinum-patterned surface, the microengine power/speed can be controlled using a white light source. A change in intensity of the white light leads to a controllable switching “off” and “on” of the microengine power on demand. Light degrades a local concentration of the hydrogen peroxide fuel and surface tension and subsequently suppresses the generation of oxygen microbubbles. In the next step, the diameter of the microjets was rigorously reduced to 250 nm by using hybrid heteroepitaxial/catalytic InGaAs/GaAs/Cr/Pt nanotubes. Due to asymmetry of the rolled-up layers, these nanojets move in corkscrew-like motions and act as “self-propelled nanotools,” which were used in the next step to transport yeast cells and drill into fixed cancer Hela cells.

2016 copyright  Prof. A.A. Solovev

Although, it is well-known that hydrogen peroxide cannot be used to sustain viable cellular function, it is however conceivable that alternative fuels, such as glucose, might enable operation of such nanotools under biologically compatible conditions. As a first step to achieve this goal, demonstrations were made using metal-enzyme biocatalytic Ti/Au/SAM/Catalase microengines. Synthetic components with competing interactions are well-suited to study the emergence of their collective behavior, such as swarms of large numbers of individuals. Microengines’ self-organization in bistable swarms is shown at the air-liquid interface of the mixture of propylene carbonate and hydrogen peroxide. Microengines act as “water striders.” Buoyed by oxygen bubbles, they self-propel via the microbubble recoiling mechanism and, depending on the bubbles’ sizes, self-organize into swarms due to the meniscus-climbing effect. These reversible swarms depend on the microengine power, which competes against attracting surface tension force. The demonstrated microjet engines show great promise for emerging applications, including biomedical, on-chip, environmental, and robotic micromachines. Furthermore, a key method discovered, entitled “rolled-up nanotechnology on polymers,” allowed for the fabrication of highly parallel arrays of microtubes with multiple functionalities and aimed for different purposes.

Professor Yongfeng Mei
Materials Science Department
Fudan University, China


Professor Gaoshan Huang
Materials Science Department
Fudan University, Shanghai


AAS Nanotechnology Group
Fudan University, Shanghai

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